A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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Rotary motion of DNA rotors on nanopores. Major row: raw video clip of the Cy5 channel of every rotor. Middle row: corresponding one-particle localization final results of both finishes of the DNA rotors. The posture of the current body is marked as orange and blue dots, plus the trajectory of the 10 frames in advance of the current body is shown as stable lines.
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To be a individual, I provide the biblical assignment to examine and use all the things in development for the advantage of my neighbour. I usually do not expertise any conflict in between faith and science. Quite the opposite, my religion stimulates me to accomplish science, to become open up-minded on the globe.’
Sadly, For a long time immediately after Iijima’s report, the creation of clean up nanotubes was cumbersome. In 1996, nevertheless, the group of Richard Smalley at Rice University managed to supply solitary-walled carbon nanotubes at large produce. Shortly soon after, I contacted Smalley, and we chose to be part of forces to evaluate the transportation via a solitary carbon nanotube.
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and first ever study with the dynamics DNA supercoils and the discovery of supercoil hopping
The coiled-coil of your human Rad50 DNA fix protein has specific segments of enhanced adaptability
Given that 2000 he moved to one-molecule biophysics and nanobiology, with analysis from DNA supercoiling studies of nucleosomes and DNA repair service proteins to DNA translocation via nanopores. Not long ago his analysis has centered on studying cell division with microbes on chip, although his top curiosity is from the path of knowing synthetic cells.
Atomic power microscopy displays that vaccinia topoisomerase IB generates filaments on DNA in the cooperative trend
Knowing basic processes regulating the spatial and dynamic organisation with the DNA in Dwell cells.
Dekker started off his exploration on solitary carbon nanotubes in 1993 when he setup a completely new line of investigate to check electrical transportation via single natural and organic molecules amongst nanoelectrodes. In 1996 a breakthrough cees dekker was recognized with carbon nanotubes. This was achieved in a very collaboration Together with the group of Nobel laureate Richard Smalley. STM and nanolithography approaches have been utilized to exhibit that these nanotubes are quantum wires at The one-molecule degree, with outstanding Bodily Qualities.
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2001, discovery of solitary-electron transistors at place temperature dependant on nanotubes; realization of first logic circuits with carbon nanotube gadgets; and discovery in the molecular construction of DNA fix enzymes with AFM
2008, first observation of protein-coated DNA translocation through nanopores; resolved the origin of the electrophoretic drive on DNA in nanopores; discovered a substantial velocity improve of microtubules in electric fields; discovered an anomalous electro-hydrodynamic orientation of microtubules; and fixed the origin of sounds in carbon nanotubes in liquid
2013, managed shaping of live bacterial cells into arbitrary designs; and discovery of spontaneous fluctuations in the handedness of histone tetrasomes